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Assessment of Inactivating Stop Codon Mutations in Forty Saccharomyces cerevisiae Strains: Implications for [PSI (+)] Prion- Mediated Phenotypes
The yeast prion [PSI (+)] has been implicated in the generation of novel phenotypes by a mechanism involving a reduction in translation fidelity causing readthrough of naturally occurring stop codons. Some [PSI (+)] associated phenotypes may also be generated due to readthrough of inactivating stop...
Autores principales: | Fitzpatrick, David A., O'Brien, Jennifer, Moran, Ciara, Hasin, Naushaba, Kenny, Elaine, Cormican, Paul, Gates, Amy, Morris, Derek W., Jones, Gary W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240633/ https://www.ncbi.nlm.nih.gov/pubmed/22194885 http://dx.doi.org/10.1371/journal.pone.0028684 |
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