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How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over

Objective To determine the speed at which the Grim Reaper (or Death) walks. Design Population based prospective study. Setting Older community dwelling men living in Sydney, Australia. Participants 1705 men aged 70 or more participating in CHAMP (Concord Health and Ageing in Men Project). Main outco...

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Autores principales: Stanaway, Fiona F, Gnjidic, Danijela, Blyth, Fiona M, Couteur, David G Le, Naganathan, Vasi, Waite, Louise, Seibel, Markus J, Handelsman, David J, Sambrook, Philip N, Cumming, Robert G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240682/
https://www.ncbi.nlm.nih.gov/pubmed/22174324
http://dx.doi.org/10.1136/bmj.d7679
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author Stanaway, Fiona F
Gnjidic, Danijela
Blyth, Fiona M
Couteur, David G Le
Naganathan, Vasi
Waite, Louise
Seibel, Markus J
Handelsman, David J
Sambrook, Philip N
Cumming, Robert G
author_facet Stanaway, Fiona F
Gnjidic, Danijela
Blyth, Fiona M
Couteur, David G Le
Naganathan, Vasi
Waite, Louise
Seibel, Markus J
Handelsman, David J
Sambrook, Philip N
Cumming, Robert G
author_sort Stanaway, Fiona F
collection PubMed
description Objective To determine the speed at which the Grim Reaper (or Death) walks. Design Population based prospective study. Setting Older community dwelling men living in Sydney, Australia. Participants 1705 men aged 70 or more participating in CHAMP (Concord Health and Ageing in Men Project). Main outcome measures Walking speed (m/s) and mortality. Receiver operating characteristics curve analysis was used to calculate the area under the curve for walking speed and determine the walking speed of the Grim Reaper. The optimal walking speed was estimated using the Youden index (sensitivity+specificity−1), a common summary measure of the receiver operating characteristics curve, and represents the maximum potential effectiveness of a marker. Results The mean walking speed was 0.88 (range 0.15-1.60) m/s. The highest Youden index (0.293) was observed at a walking speed of 0.82 m/s (2 miles (about 3 km) per hour), corresponding to a sensitivity of 63% and a specificity of 70% for mortality. Survival analysis showed that older men who walked faster than 0.82 m/s were 1.23 times less likely to die (95% confidence interval 1.10 to 1.37) than those who walked slower (P=0.0003). A sensitivity of 1.0 was obtained when a walking speed of 1.36 m/s (3 miles (about 5 km) per hour) or greater was used, indicating that no men with walking speeds of 1.36 m/s or greater had contact with Death. Conclusion The Grim Reaper’s preferred walking speed is 0.82 m/s (2 miles (about 3 km) per hour) under working conditions. As none of the men in the study with walking speeds of 1.36 m/s (3 miles (about 5 km) per hour) or greater had contact with Death, this seems to be the Grim Reaper’s most likely maximum speed; for those wishing to avoid their allotted fate, this would be the advised walking speed.
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spelling pubmed-32406822011-12-16 How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over Stanaway, Fiona F Gnjidic, Danijela Blyth, Fiona M Couteur, David G Le Naganathan, Vasi Waite, Louise Seibel, Markus J Handelsman, David J Sambrook, Philip N Cumming, Robert G BMJ Research Objective To determine the speed at which the Grim Reaper (or Death) walks. Design Population based prospective study. Setting Older community dwelling men living in Sydney, Australia. Participants 1705 men aged 70 or more participating in CHAMP (Concord Health and Ageing in Men Project). Main outcome measures Walking speed (m/s) and mortality. Receiver operating characteristics curve analysis was used to calculate the area under the curve for walking speed and determine the walking speed of the Grim Reaper. The optimal walking speed was estimated using the Youden index (sensitivity+specificity−1), a common summary measure of the receiver operating characteristics curve, and represents the maximum potential effectiveness of a marker. Results The mean walking speed was 0.88 (range 0.15-1.60) m/s. The highest Youden index (0.293) was observed at a walking speed of 0.82 m/s (2 miles (about 3 km) per hour), corresponding to a sensitivity of 63% and a specificity of 70% for mortality. Survival analysis showed that older men who walked faster than 0.82 m/s were 1.23 times less likely to die (95% confidence interval 1.10 to 1.37) than those who walked slower (P=0.0003). A sensitivity of 1.0 was obtained when a walking speed of 1.36 m/s (3 miles (about 5 km) per hour) or greater was used, indicating that no men with walking speeds of 1.36 m/s or greater had contact with Death. Conclusion The Grim Reaper’s preferred walking speed is 0.82 m/s (2 miles (about 3 km) per hour) under working conditions. As none of the men in the study with walking speeds of 1.36 m/s (3 miles (about 5 km) per hour) or greater had contact with Death, this seems to be the Grim Reaper’s most likely maximum speed; for those wishing to avoid their allotted fate, this would be the advised walking speed. BMJ Publishing Group Ltd. 2011-12-15 /pmc/articles/PMC3240682/ /pubmed/22174324 http://dx.doi.org/10.1136/bmj.d7679 Text en © Stanaway et al 2011 This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode.
spellingShingle Research
Stanaway, Fiona F
Gnjidic, Danijela
Blyth, Fiona M
Couteur, David G Le
Naganathan, Vasi
Waite, Louise
Seibel, Markus J
Handelsman, David J
Sambrook, Philip N
Cumming, Robert G
How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over
title How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over
title_full How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over
title_fullStr How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over
title_full_unstemmed How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over
title_short How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over
title_sort how fast does the grim reaper walk? receiver operating characteristics curve analysis in healthy men aged 70 and over
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240682/
https://www.ncbi.nlm.nih.gov/pubmed/22174324
http://dx.doi.org/10.1136/bmj.d7679
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