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How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over
Objective To determine the speed at which the Grim Reaper (or Death) walks. Design Population based prospective study. Setting Older community dwelling men living in Sydney, Australia. Participants 1705 men aged 70 or more participating in CHAMP (Concord Health and Ageing in Men Project). Main outco...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240682/ https://www.ncbi.nlm.nih.gov/pubmed/22174324 http://dx.doi.org/10.1136/bmj.d7679 |
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author | Stanaway, Fiona F Gnjidic, Danijela Blyth, Fiona M Couteur, David G Le Naganathan, Vasi Waite, Louise Seibel, Markus J Handelsman, David J Sambrook, Philip N Cumming, Robert G |
author_facet | Stanaway, Fiona F Gnjidic, Danijela Blyth, Fiona M Couteur, David G Le Naganathan, Vasi Waite, Louise Seibel, Markus J Handelsman, David J Sambrook, Philip N Cumming, Robert G |
author_sort | Stanaway, Fiona F |
collection | PubMed |
description | Objective To determine the speed at which the Grim Reaper (or Death) walks. Design Population based prospective study. Setting Older community dwelling men living in Sydney, Australia. Participants 1705 men aged 70 or more participating in CHAMP (Concord Health and Ageing in Men Project). Main outcome measures Walking speed (m/s) and mortality. Receiver operating characteristics curve analysis was used to calculate the area under the curve for walking speed and determine the walking speed of the Grim Reaper. The optimal walking speed was estimated using the Youden index (sensitivity+specificity−1), a common summary measure of the receiver operating characteristics curve, and represents the maximum potential effectiveness of a marker. Results The mean walking speed was 0.88 (range 0.15-1.60) m/s. The highest Youden index (0.293) was observed at a walking speed of 0.82 m/s (2 miles (about 3 km) per hour), corresponding to a sensitivity of 63% and a specificity of 70% for mortality. Survival analysis showed that older men who walked faster than 0.82 m/s were 1.23 times less likely to die (95% confidence interval 1.10 to 1.37) than those who walked slower (P=0.0003). A sensitivity of 1.0 was obtained when a walking speed of 1.36 m/s (3 miles (about 5 km) per hour) or greater was used, indicating that no men with walking speeds of 1.36 m/s or greater had contact with Death. Conclusion The Grim Reaper’s preferred walking speed is 0.82 m/s (2 miles (about 3 km) per hour) under working conditions. As none of the men in the study with walking speeds of 1.36 m/s (3 miles (about 5 km) per hour) or greater had contact with Death, this seems to be the Grim Reaper’s most likely maximum speed; for those wishing to avoid their allotted fate, this would be the advised walking speed. |
format | Online Article Text |
id | pubmed-3240682 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BMJ Publishing Group Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-32406822011-12-16 How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over Stanaway, Fiona F Gnjidic, Danijela Blyth, Fiona M Couteur, David G Le Naganathan, Vasi Waite, Louise Seibel, Markus J Handelsman, David J Sambrook, Philip N Cumming, Robert G BMJ Research Objective To determine the speed at which the Grim Reaper (or Death) walks. Design Population based prospective study. Setting Older community dwelling men living in Sydney, Australia. Participants 1705 men aged 70 or more participating in CHAMP (Concord Health and Ageing in Men Project). Main outcome measures Walking speed (m/s) and mortality. Receiver operating characteristics curve analysis was used to calculate the area under the curve for walking speed and determine the walking speed of the Grim Reaper. The optimal walking speed was estimated using the Youden index (sensitivity+specificity−1), a common summary measure of the receiver operating characteristics curve, and represents the maximum potential effectiveness of a marker. Results The mean walking speed was 0.88 (range 0.15-1.60) m/s. The highest Youden index (0.293) was observed at a walking speed of 0.82 m/s (2 miles (about 3 km) per hour), corresponding to a sensitivity of 63% and a specificity of 70% for mortality. Survival analysis showed that older men who walked faster than 0.82 m/s were 1.23 times less likely to die (95% confidence interval 1.10 to 1.37) than those who walked slower (P=0.0003). A sensitivity of 1.0 was obtained when a walking speed of 1.36 m/s (3 miles (about 5 km) per hour) or greater was used, indicating that no men with walking speeds of 1.36 m/s or greater had contact with Death. Conclusion The Grim Reaper’s preferred walking speed is 0.82 m/s (2 miles (about 3 km) per hour) under working conditions. As none of the men in the study with walking speeds of 1.36 m/s (3 miles (about 5 km) per hour) or greater had contact with Death, this seems to be the Grim Reaper’s most likely maximum speed; for those wishing to avoid their allotted fate, this would be the advised walking speed. BMJ Publishing Group Ltd. 2011-12-15 /pmc/articles/PMC3240682/ /pubmed/22174324 http://dx.doi.org/10.1136/bmj.d7679 Text en © Stanaway et al 2011 This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode. |
spellingShingle | Research Stanaway, Fiona F Gnjidic, Danijela Blyth, Fiona M Couteur, David G Le Naganathan, Vasi Waite, Louise Seibel, Markus J Handelsman, David J Sambrook, Philip N Cumming, Robert G How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over |
title | How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over |
title_full | How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over |
title_fullStr | How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over |
title_full_unstemmed | How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over |
title_short | How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over |
title_sort | how fast does the grim reaper walk? receiver operating characteristics curve analysis in healthy men aged 70 and over |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240682/ https://www.ncbi.nlm.nih.gov/pubmed/22174324 http://dx.doi.org/10.1136/bmj.d7679 |
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