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Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPD
RATIONALE: Muscle atrophy confers a poor prognosis in patients with chronic obstructive pulmonary disease (COPD), yet the molecular pathways responsible are poorly characterised. Muscle-specific microRNAs and serum response factor (SRF) are important regulators of muscle phenotype that contribute to...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240776/ https://www.ncbi.nlm.nih.gov/pubmed/21998125 http://dx.doi.org/10.1136/thoraxjnl-2011-200309 |