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Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPD

RATIONALE: Muscle atrophy confers a poor prognosis in patients with chronic obstructive pulmonary disease (COPD), yet the molecular pathways responsible are poorly characterised. Muscle-specific microRNAs and serum response factor (SRF) are important regulators of muscle phenotype that contribute to...

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Detalles Bibliográficos
Autores principales:	Lewis, Amy, Riddoch-Contreras, Joanna, Natanek, Samantha A, Donaldson, Anna, Man, William D-C, Moxham, John, Hopkinson, Nicholas S, Polkey, Michael I, Kemp, Paul R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Group 2011
Materias:	Chronic Obstructive Pulmonary Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240776/ https://www.ncbi.nlm.nih.gov/pubmed/21998125 http://dx.doi.org/10.1136/thoraxjnl-2011-200309

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