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NONO and RALY proteins are required for YB-1 oxaliplatin induced resistance in colon adenocarcinoma cell lines

BACKGROUND: YB-1 is a multifunctional protein that affects transcription, splicing, and translation. Overexpression of YB-1 in breast cancers causes cisplatin resistance. Recent data have shown that YB-1 is also overexpress in colorectal cancer. In this study, we tested the hypothesis that YB-1 also...

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Detalles Bibliográficos
Autores principales: Tsofack, Serges P, Garand, Chantal, Sereduk, Chris, Chow, Donald, Aziz, Meraj, Guay, David, Yin, Hongwei H, Lebel, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240900/
https://www.ncbi.nlm.nih.gov/pubmed/22118625
http://dx.doi.org/10.1186/1476-4598-10-145