Cargando…

Structural insights into thioredoxin-2: a component of malaria parasite protein secretion machinery

Thioredoxins are vital components of Plasmodium proteome and act as both reducing agents and protein disulfide reductases. The malaria parasite P. falciparum thioredoxin-2 (PfTrx-2) is part of the multi-protein complex embedded within the parasite parasitophorous vacuolar membrane (PVM) which purpor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sharma, Ashwani, Sharma, Arvind, Dixit, Sameer, Sharma, Amit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240959/ https://www.ncbi.nlm.nih.gov/pubmed/22355694 http://dx.doi.org/10.1038/srep00179

Ejemplares similares

Structural and functional attributes of malaria parasite diadenosine tetraphosphate hydrolase
por: Sharma, Arvind, et al.
Publicado: (2016)

Crystal Structure of Soluble Domain of Malaria Sporozoite Protein UIS3 in Complex with Lipid
por: Sharma, Ashwani, et al.
Publicado: (2008)

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery
por: Patel, Avnish, et al.
Publicado: (2019)

The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites
por: De Niz, Mariana, et al.
Publicado: (2016)

siRNA Machinery in Whitefly (Bemisia tabaci)
por: Upadhyay, Santosh Kumar, et al.
Publicado: (2013)

Crystal Structure of Malaria Parasite Nucleosome Assembly Protein: DISTINCT MODES OF PROTEIN LOCALIZATION AND HISTONE RECOGNITION
por: Gill, Jasmita, et al.
Publicado: (2009)

An Appended Domain Results in an Unusual Architecture for Malaria Parasite Tryptophanyl-tRNA Synthetase
por: Khan, Sameena, et al.
Publicado: (2013)

Genomic analysis of single nucleotide polymorphisms in malaria parasite drug targets
por: Gill, Jasmita, et al.
Publicado: (2022)

Cell Signaling with Extracellular Thioredoxin and Thioredoxin-Like Proteins: Insight into Their Mechanisms of Action
por: Léveillard, Thierry, et al.
Publicado: (2017)

Alternative Protein Secretion in the Malaria Parasite Plasmodium falciparum
por: Thavayogarajah, Thuvaraka, et al.
Publicado: (2015)

The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
por: Hwang, Jungwon, et al.
Publicado: (2014)

Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines
por: Sharma, Manmohan, et al.
Publicado: (2021)

Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites
por: Mishra, Prakash Chandra, et al.
Publicado: (2009)

Horizontal gene transfer of epigenetic machinery and evolution of parasitism in the malaria parasite Plasmodium falciparum and other apicomplexans
por: Kishore, Sandeep P, et al.
Publicado: (2013)

In silico Study of Iron, Zinc and Copper Binding Proteins of Pseudomonas syringae pv. lapsa: Emphasis on Secreted Metalloproteins
por: Sharma, Ankita, et al.
Publicado: (2018)

Systematic Dissection of the Agrobacterium Type VI Secretion System Reveals Machinery and Secreted Components for Subcomplex Formation
por: Lin, Jer-Sheng, et al.
Publicado: (2013)

A genomic glimpse of aminoacyl-tRNA synthetases in malaria parasite Plasmodium falciparum
por: Bhatt, Tarun Kumar, et al.
Publicado: (2009)

A Novel Thioredoxin-Like Protein of Babesia microti Involved in Parasite Pathogenicity
por: Piao, Xianyu, et al.
Publicado: (2022)

Structural and Functional Insights into the Malaria Parasite Moving Junction Complex
por: Vulliez-Le Normand, Brigitte, et al.
Publicado: (2012)

An unusual thioredoxin system in the facultative parasite Acanthamoeba castellanii
por: Leitsch, David, et al.
Publicado: (2021)

Characterization of the Ubiquitylating Components of the Human Malaria Parasite’s Protein Degradation Pathway
por: Chung, Duk-Won D., et al.
Publicado: (2012)

Parasite Killing in Malaria Non-Vector Mosquito Anopheles culicifacies Species B: Implication of Nitric Oxide Synthase Upregulation
por: Vijay, Sonam, et al.
Publicado: (2011)

Thioredoxin reductase: An emerging pharmacologic target for radiosensitization of cancer
por: Patwardhan, Raghavendra S., et al.
Publicado: (2022)

Cerebral malaria: insights from host-parasite protein-protein interactions
por: Rao, Aditya, et al.
Publicado: (2010)

Surveillance based estimation of burden of malaria in India, 2015–2016
por: Kumar, Ashwani, et al.
Publicado: (2020)

Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles
por: Verma, Ruchi, et al.
Publicado: (2008)

Structural insights into reptarenavirus cap-snatching machinery
por: Rosenthal, Maria, et al.
Publicado: (2017)

Role of Plasmodium falciparum thrombospondin-related anonymous protein in host-cell interactions
por: Akhouri, Reetesh Raj, et al.
Publicado: (2008)

Machinery component maintenance and repair
por: Bloch, Heinz P, et al.
Publicado: (2019)

Membrane and luminal proteins reach the apicoplast by different trafficking pathways in the malaria parasite Plasmodium falciparum
por: Chaudhari, Rahul, et al.
Publicado: (2017)

Phosphorylation of Rhoptry Protein RhopH3 Is Critical for Host Cell Invasion by the Malaria Parasite
por: Ekka, Roseleen, et al.
Publicado: (2020)

Climate zones are a key component of the heterogeneous presentation of malaria and should be added as a malariometric for the planning of malaria elimination
por: Yadav, Chander Prakash, et al.
Publicado: (2023)

Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths
por: Otero, Lucía, et al.
Publicado: (2010)

New drug target in protozoan parasites: the role of thioredoxin reductase
por: Andrade, Rosa M., et al.
Publicado: (2015)

Structural insights into chondroitin sulphate A binding Duffy-binding-like domains from Plasmodium falciparum: implications for intervention strategies against placental malaria
por: Gill, Jasmita, et al.
Publicado: (2009)

Insights into age- and sickle-cell-disease- interaction using principal components analysis
por: Sharma, Mamta, et al.
Publicado: (2006)

Thioredoxin Profiling of Multiple Thioredoxin-Like Proteins in Staphylococcus aureus
por: Peng, Hui, et al.
Publicado: (2018)

Signaling Strategies of Malaria Parasite for Its Survival, Proliferation, and Infection during Erythrocytic Stage
por: Soni, Rani, et al.
Publicado: (2017)

From DNA to proteins via the ribosome: Structural insights into the workings of the translation machinery
por: Agirrezabala, Xabier, et al.
Publicado: (2010)

The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasites
por: Looker, Oliver, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jc51vprf4fu7ntpu92rqpk77mt