Cargando…

Rational Design of Pathogen-Mimicking Amphiphilic Materials as Nanoadjuvants

An opportunity exists today for cross-cutting research utilizing advances in materials science, immunology, microbial pathogenesis, and computational analysis to effectively design the next generation of adjuvants and vaccines. This study integrates these advances into a bottom-up approach for the m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ulery, Bret D., Petersen, Latrisha K., Phanse, Yashdeep, Kong, Chang Sun, Broderick, Scott R., Kumar, Devender, Ramer-Tait, Amanda E., Carrillo-Conde, Brenda, Rajan, Krishna, Wannemuehler, Michael J., Bellaire, Bryan H., Metzger, Dennis W., Narasimhan, Balaji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240970/ https://www.ncbi.nlm.nih.gov/pubmed/22355713 http://dx.doi.org/10.1038/srep00198

Ejemplares similares

Design of a Protective Single-Dose Intranasal Nanoparticle-Based Vaccine Platform for Respiratory Infectious Diseases
por: Ulery, Bret D., et al.
Publicado: (2011)

A systems approach to designing next generation vaccines: combining α-galactose modified antigens with nanoparticle platforms
por: Phanse, Yashdeep, et al.
Publicado: (2014)

Combinatorial evaluation of in vivo distribution of polyanhydride particle-based platforms for vaccine delivery
por: Petersen, Latrisha K, et al.
Publicado: (2013)

Novel nanoadjuvants balance immune activation with modest inflammation: implications for older adult vaccines
por: Ross, Kathleen A., et al.
Publicado: (2023)

Synthesis and Optimization of Next-Generation Low-Molecular-Weight Pentablock Copolymer Nanoadjuvants
por: Siddoway, Alaric C., et al.
Publicado: (2023)

Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8(+) T Cell Memory and Delayed Tumor Progression
por: Darling, Ross, et al.
Publicado: (2020)

Recent Patents on Nasal Vaccines Containing Nanoadjuvants
por: Candela, Francesco, et al.
Publicado: (2022)

Self-assembling synthetic nanoadjuvant scaffolds cross-link B cell receptors and represent new platform technology for therapeutic antibody production
por: Senapati, Sujata, et al.
Publicado: (2021)

RNA Nanovaccine Protects against White Spot Syndrome Virus in Shrimp
por: Phanse, Yashdeep, et al.
Publicado: (2022)

Nanoadjuvants: Promising Bioinspired and Biomimetic Approaches in Vaccine Innovation
por: Desai, Dhruv N., et al.
Publicado: (2023)

Physicochemical Characterization Cascade of Nanoadjuvant–Antigen Systems for Improving Vaccines
por: Guerrini, Giuditta, et al.
Publicado: (2021)

Manganese-based nanoadjuvants for enhancement of immune effect of DNA vaccines
por: Ma, Qiang, et al.
Publicado: (2022)

Impact of Hydrophobic Chain Composition on Amphiphilic Macromolecule Antiatherogenic Bioactivity
por: Faig, Allison, et al.
Publicado: (2014)

Biodistribution of degradable polyanhydride particles in Aedes aegypti tissues
por: Norris, Edmund J., et al.
Publicado: (2020)

A single dose polyanhydride-based nanovaccine against paratuberculosis infection
por: Thukral, Akanksha, et al.
Publicado: (2020)

Amphiphilic polyanhydride-based recombinant MUC4β-nanovaccine activates dendritic cells
por: Banerjee, Kasturi, et al.
Publicado: (2019)

A versatile supramolecular nanoadjuvant that activates NF-κB for cancer immunotherapy
por: Xu, Yan, et al.
Publicado: (2019)

High Molecular Weight Chitosan-Complexed RNA Nanoadjuvant for Effective Cancer Immunotherapy
por: Choi, Jin Joo, et al.
Publicado: (2019)

Silicone Oil-Based Nanoadjuvants as Candidates for a New Formulation of Intranasal Vaccines
por: Razim, Agnieszka, et al.
Publicado: (2021)

Iodine-Rich Nanoadjuvants for CT Imaging–Guided Photodynamic Immunotherapy of Breast Cancer
por: Xin, Xiaoyan, et al.
Publicado: (2022)

Biocompatibility and Characterization of a Peptide Amphiphile Hydrogel for Applications in Peripheral Nerve Regeneration
por: Black, Katie A., et al.
Publicado: (2015)

An In Vitro Model of Antibody-Enhanced Killing of the Intracellular Parasite Leishmania amazonensis
por: Gibson-Corley, Katherine N., et al.
Publicado: (2014)

Fabrication of nanoadjuvant with poly-ε-caprolactone (PCL) for developing a single-shot vaccine providing prolonged immunity
por: Prashant, Chandravilas Keshvan, et al.
Publicado: (2014)

Regulating the surface topography of CpG nanoadjuvants via coordination-driven self-assembly for enhanced tumor immunotherapy
por: Zhang, Li, et al.
Publicado: (2023)

Amphiphilic Nanoparticles Repress Macrophage Atherogenesis: Novel Core/Shell Designs for Scavenger Receptor Targeting and Down-Regulation
por: Petersen, Latrisha K., et al.
Publicado: (2014)

Fabrication of nanoadjuvant with poly-ε-caprolactone (PCL) for developing a single-shot vaccine providing prolonged immunity [Corrigendum]
Publicado: (2014)

SPIO Enhance the Cross-Presentation and Migration of DCs and Anionic SPIO Influence the Nanoadjuvant Effects Related to Interleukin-1β
por: Liu, Hui, et al.
Publicado: (2018)

Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity
por: Ross, Kathleen A, et al.
Publicado: (2014)

Universal selenium nanoadjuvant with immunopotentiating and redox-shaping activities inducing high-quality immunity for SARS-CoV-2 vaccine
por: Lai, Haoqiang, et al.
Publicado: (2023)

A Protective Vaccine against Johne’s Disease in Cattle
por: Phanse, Yashdeep, et al.
Publicado: (2020)

Gut Organoid as a New Platform to Study Alginate and Chitosan Mediated PLGA Nanoparticles for Drug Delivery
por: Davoudi, Zahra, et al.
Publicado: (2021)

Polyanhydride Nanoparticle Delivery Platform Dramatically Enhances Killing of Filarial Worms
por: Binnebose, Andrea M., et al.
Publicado: (2015)

Rational Design of Amphiphilic Diblock Copolymer/MWCNT Surface Modifiers and Their Application for Direct Electrochemical Sensing of DNA
por: Sigolaeva, Larisa V., et al.
Publicado: (2020)

Room Temperature Stable PspA-Based Nanovaccine Induces Protective Immunity
por: Wagner-Muñiz, Danielle A., et al.
Publicado: (2018)

Protective RNA nanovaccines against Mycobacterium avium subspecies hominissuis
por: Touray, Bubacarr J.B., et al.
Publicado: (2023)

A Comparative Analysis of RNAi Trigger Uptake and Distribution in Mosquito Vectors of Disease
por: Airs, Paul M., et al.
Publicado: (2023)

Temporal Dynamics of Chronic Inflammation on the Cecal Microbiota in IL-10(-/-) Mice
por: Overstreet, Anne-Marie C., et al.
Publicado: (2021)

Aggregation of p-Sulfonatocalixarene-Based Amphiphiles and Supra-Amphiphiles
por: Basilio, Nuno, et al.
Publicado: (2013)

Activation of apoptosis by rationally constructing NIR amphiphilic AIEgens: surmounting the shackle of mitochondrial membrane potential for amplified tumor ablation
por: Li, Haidong, et al.
Publicado: (2021)

Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma(☆)
por: Chung, Eun Ji, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_lhdoso0snoed6o8cj4ga2hnjsq