Cargando…
Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-kappaB-dependent pathway
INTRODUCTION: Methotrexate (MTX) induces macrophage apoptosis in vitro, but there is not much evidence for increased synovial macrophage apoptosis in MTX-treated patients. Macrophage apoptosis is reported, however, during clinical response to anti-tumor necrosis factor-alpha (TNF-α) treatments. This...
Autores principales: | Lo, Susan ZY, Steer, James H, Joyce, David A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241368/ https://www.ncbi.nlm.nih.gov/pubmed/21324111 http://dx.doi.org/10.1186/ar3248 |
Ejemplares similares
-
NF-kappaB in Lung Tumorigenesis
por: Cai, Zhenjian, et al.
Publicado: (2011) -
NF-kappaB mediates the survival of human bronchial epithelial cells exposed to cigarette smoke extract
por: Liu, Xiangde, et al.
Publicado: (2008) -
Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis.
por: Jue, D. M., et al.
Publicado: (1999) -
NF-kappaB and cytokines in pancreatic acinar cells.
por: Kim, H, et al.
Publicado: (2000) -
NF-kappaB: Two Sides of the Same Coin
por: Pires, Bruno R. B., et al.
Publicado: (2018)