Reduced immunomodulation potential of bone marrow-derived mesenchymal stem cells induced CCR4(+)CCR6(+ )Th/Treg cell subset imbalance in ankylosing spondylitis

INTRODUCTION: Ankylosing spondylitis (AS) is a chronic autoimmune disease, and the precise pathogenesis is largely unknown at present. Bone marrow-derived mesenchymal stem cells (BMSCs) with immunosuppressive and anti-inflammatory potential and Th17/Treg cells with a reciprocal relationship regulate...

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Detalles Bibliográficos
Autores principales: Wu, Yanfeng, Ren, Mingliang, Yang, Rui, Liang, Xinjun, Ma, Yuanchen, Tang, Yong, Huang, Lin, Ye, Jichao, Chen, Keng, Wang, Peng, Shen, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241373/
https://www.ncbi.nlm.nih.gov/pubmed/21338515
http://dx.doi.org/10.1186/ar3257

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