Association of rib anomalies and childhood cancers

BACKGROUND: Congenital anomalies have been found more often in children with cancer than in those without. Rib abnormalities (RAs) have been associated with childhood cancer; however, studies have differed in the type of RAs and cancers implicated. METHODS: Rib abnormalities were assessed predominan...

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Detalles Bibliográficos
Autores principales: Zierhut, H, Murati, M, Holm, T, Hoggard, E, Spector, L G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241545/
https://www.ncbi.nlm.nih.gov/pubmed/21915120
http://dx.doi.org/10.1038/bjc.2011.366
Descripción
Sumario:BACKGROUND: Congenital anomalies have been found more often in children with cancer than in those without. Rib abnormalities (RAs) have been associated with childhood cancer; however, studies have differed in the type of RAs and cancers implicated. METHODS: Rib abnormalities were assessed predominantly by X-ray in a hospital-based case–control study. RESULTS: There was a significant difference in the number of cases vs controls with RAs after controlling for age and sex, specifically for acute myelogenous leukaemia, renal tumours, and hepatoblastoma. CONCLUSION: The results of this study support previous reports that there is an association of rib anomalies with childhood cancer.

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