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PTEN regulates colorectal epithelial apoptosis through Cdc42 signalling

BACKGROUND: Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) regulation of the Rho-like GTPase Cdc42 has a central role in epithelial polarised growth, but effects of this molecular network on apoptosis remain unclear. METHODS: To investigate the role of Cdc42 in PTEN-dependent cell...

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Detalles Bibliográficos
Autores principales:	Deevi, R, Fatehullah, A, Jagan, I, Nagaraju, M, Bingham, V, Campbell, F C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241554/ https://www.ncbi.nlm.nih.gov/pubmed/21952626 http://dx.doi.org/10.1038/bjc.2011.384

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