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Synergistic Antitumor Effects of Novel HDAC Inhibitors and Paclitaxel In Vitro and In Vivo

Preclinical studies support the therapeutic potential of histone deacetylases inhibitors (HDACi) in combination with taxanes. The efficacy of combination has been mainly ascribed to a cooperative effect on microtubule stabilization following tubulin acetylation. In the present study we investigated...

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Detalles Bibliográficos
Autores principales:	Zuco, Valentina, De Cesare, Michelandrea, Cincinelli, Raffaella, Nannei, Raffaella, Pisano, Claudio, Zaffaroni, Nadia, Zunino, Franco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241602/ https://www.ncbi.nlm.nih.gov/pubmed/22194993 http://dx.doi.org/10.1371/journal.pone.0029085

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