A single methyltransferase YefA (RlmCD) catalyses both m(5)U747 and m(5)U1939 modifications in Bacillus subtilis 23S rRNA

Methyltransferases that use S-adenosylmethionine (AdoMet) as a cofactor to catalyse 5-methyl uridine (m(5)U) formation in tRNAs and rRNAs are widespread in Bacteria and Eukaryota, and are also found in certain Archaea. These enzymes belong to the COG2265 cluster, and the Gram-negative bacterium Esch...

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Detalles Bibliográficos
Autores principales: Desmolaize, Benoit, Fabret, Céline, Brégeon, Damien, Rose, Simon, Grosjean, Henri, Douthwaite, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241648/
https://www.ncbi.nlm.nih.gov/pubmed/21824914
http://dx.doi.org/10.1093/nar/gkr626

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