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Nuclear hormone 1α,25-dihydroxyvitamin D(3) elicits a genome-wide shift in the locations of VDR chromatin occupancy
A global understanding of the actions of the nuclear hormone 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)) and its vitamin D receptor (VDR) requires a genome-wide analysis of VDR binding sites. In THP-1 human monocytic leukemia cells we identified by ChIP-seq 2340 VDR binding locations, of which 11...
Autores principales: | Heikkinen, Sami, Väisänen, Sami, Pehkonen, Petri, Seuter, Sabine, Benes, Vladimir, Carlberg, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241659/ https://www.ncbi.nlm.nih.gov/pubmed/21846776 http://dx.doi.org/10.1093/nar/gkr654 |
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