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Characterization of the DNA binding specificity of Shelterin complexes

The Shelterin complex associates with telomeres and plays an essential role in telomere protection and telomerase regulation. In its most abundant form, the complex is composed of six core components: TRF1, TRF2, POT1, TIN2, TPP1 and RAP1. Of these subunits, three can interact directly with either s...

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Detalles Bibliográficos
Autores principales: Choi, Kyung H., Farrell, Amy S., Lakamp, Amanda S., Ouellette, Michel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241663/
https://www.ncbi.nlm.nih.gov/pubmed/21852327
http://dx.doi.org/10.1093/nar/gkr665