Cargando…

AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice

Brain inflammation is a double-edged sword: it is required for brain repair in acute damage, whereas chronic inflammation and autoimmune disorders are neuropathogenic. Certain pro-inflammatory cytokines and chemokines are closely related to cognitive dysfunction and neurodegeneration. Representative...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kiyota, Tomomi, Ingraham, Kaitlin L., Swan, Russell J., Jacobsen, Michael T., Andrews, Scott J., Ikezu, Tsuneya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241853/ https://www.ncbi.nlm.nih.gov/pubmed/21918553 http://dx.doi.org/10.1038/gt.2011.126

Ejemplares similares

Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models
por: Ikezu, Seiko, et al.
Publicado: (2020)

Microglial WNT5A supports dendritic spines maturation and neuronal firing
por: Yeh, Hana, et al.
Publicado: (2023)

Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice
por: Yukawa, Kayo, et al.
Publicado: (2023)

Electroacupuncture decreases cognitive impairment and promotes neurogenesis in the APP/PS1 transgenic mice
por: Li, Xuying, et al.
Publicado: (2014)

Tau-tubulin kinase
por: Ikezu, Seiko, et al.
Publicado: (2014)

Relative persistence of AAV serotype 1 vector genomes in dystrophic muscle
por: Pacak, Christina A, et al.
Publicado: (2008)

Treadmill Exercise Ameliorates Adult Hippocampal Neurogenesis Possibly by Adjusting the APP Proteolytic Pathway in APP/PS1 Transgenic Mice
por: Yu, Haizhen, et al.
Publicado: (2021)

CCL2 Accelerates Microglia-Mediated Aβ Oligomer Formation and Progression of Neurocognitive Dysfunction
por: Kiyota, Tomomi, et al.
Publicado: (2009)

Intracranial Injection of AAV Expressing NEP but Not IDE Reduces Amyloid Pathology in APP+PS1 Transgenic Mice
por: Carty, Nikisha, et al.
Publicado: (2013)

AAV ablates neurogenesis in the adult murine hippocampus
por: Johnston, Stephen, et al.
Publicado: (2021)

Cucurbitacin B induces neurogenesis in PC12 cells and protects memory in APP/PS1 mice
por: Li, Jing, et al.
Publicado: (2019)

Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model
por: Clayton, Kevin, et al.
Publicado: (2021)

Correction to: Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model
por: Clayton, Kevin, et al.
Publicado: (2021)

AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes
por: Hui, Daniel J, et al.
Publicado: (2015)

Syk and Yea Shall Find
por: Wolozin, Benjamin, et al.
Publicado: (2015)

Corrigendum to “Syk and ye shall find” [EBioMedicine 2 (11) (2015) 190-1591]
por: Wolozin, Benjamin, et al.
Publicado: (2016)

Neurogenesis, Neurodegeneration, Interneuron Vulnerability, and Amyloid-β in the Olfactory Bulb of APP/PS1 Mouse Model of Alzheimer's Disease
por: De la Rosa-Prieto, Carlos, et al.
Publicado: (2016)

20(S)-protopanaxadiol and oleanolic acid ameliorate cognitive deficits in APP/PS1 transgenic mice by enhancing hippocampal neurogenesis
por: Lin, Kaili, et al.
Publicado: (2021)

Active constituent of Polygala tenuifolia attenuates cognitive deficits by rescuing hippocampal neurogenesis in APP/PS1 transgenic mice
por: Wang, Xiao-feng, et al.
Publicado: (2021)

Global Seroprevalence of Pre-existing Immunity Against AAV5 and Other AAV Serotypes in People with Hemophilia A
por: Klamroth, Robert, et al.
Publicado: (2022)

Early-Life Stress Does Not Aggravate Spatial Memory or the Process of Hippocampal Neurogenesis in Adult and Middle-Aged APP/PS1 Mice
por: Hoeijmakers, Lianne, et al.
Publicado: (2018)

Thermal Stability as a Determinant of AAV Serotype Identity
por: Bennett, Antonette, et al.
Publicado: (2017)

Various AAV Serotypes and Their Applications in Gene Therapy: An Overview
por: Issa, Shaza S., et al.
Publicado: (2023)

Adeno-associated Virus (AAV) Serotypes Have Distinctive Interactions with Domains of the Cellular AAV Receptor
por: Pillay, Sirika, et al.
Publicado: (2017)

Improved adeno-associated virus (AAV) serotype 1 and 5 vectors for gene therapy
por: Sen, Dwaipayan, et al.
Publicado: (2013)

Preferred transduction with AAV8 and AAV9 via thalamic administration in the MPS IIIB model: A comparison of four rAAV serotypes
por: Gilkes, J.A., et al.
Publicado: (2015)

Real-Time Imaging and Quantification of Amyloid-β Peptide Aggregates by Novel Quantum-Dot Nanoprobes
por: Tokuraku, Kiyotaka, et al.
Publicado: (2009)

Serotype-specific Binding Properties and Nanoparticle Characteristics Contribute to the Immunogenicity of rAAV1 Vectors
por: Ferrand, Maxime, et al.
Publicado: (2015)

Universal Method for the Purification of Recombinant AAV Vectors of Differing Serotypes
por: Nass, Shelley A., et al.
Publicado: (2017)

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina
por: Hickey, D G, et al.
Publicado: (2017)

Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model
por: Barber-Singh, Jennifer, et al.
Publicado: (2010)

Switching of serotype can improve local AAV-mediated gene therapy in RA
por: Adriaansen, J, et al.
Publicado: (2004)

Efficacy of AAV serotypes to target Schwann cells after intrathecal and intravenous delivery
por: Kagiava, A., et al.
Publicado: (2021)

Cellular and Tissue Selectivity of AAV Serotypes for Gene Delivery to Chondrocytes and Cartilage
por: Yoon, Dong Suk, et al.
Publicado: (2021)

High-efficiency purification of divergent AAV serotypes using AAVX affinity chromatography
por: Florea, Michael, et al.
Publicado: (2022)

AAV2/1 CD74 Gene Transfer Reduces β-amyloidosis and Improves Learning and Memory in a Mouse Model of Alzheimer's Disease
por: Kiyota, Tomomi, et al.
Publicado: (2015)

Effects of Broussonetia papyrifera (L.) L'Hér. ex Vent. fruits water extract on hippocampal neurogenesis in the treatment of APP/PS1 transgenic mice
por: Yan, Yu-hui, et al.
Publicado: (2022)

Integrated Expression Profiles of mRNA and miRNA in Polarized Primary Murine Microglia
por: Freilich, Robert W., et al.
Publicado: (2013)

Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer’s Disease Patients: A Pilot Study
por: Muraoka, Satoshi, et al.
Publicado: (2020)

Immune senescence in aged APP/PS1 mice
por: Abdelmoaty, Mai M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e5a6kf657bg51mbsoj4v12mtqn