Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs

Cell transformation assays (CTAs) have long been proposed as in vitro methods for the identification of potential chemical carcinogens. Despite showing good correlation with rodent bioassay data, concerns over the subjective nature of using morphological criteria for identifying transformed cells an...

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Detalles Bibliográficos
Autores principales: Creton, Stuart, Aardema, Marilyn J., Carmichael, Paul L., Harvey, James S., Martin, Francis L., Newbold, Robert F., O’Donovan, Michael R., Pant, Kamala, Poth, Albrecht, Sakai, Ayako, Sasaki, Kiyoshi, Scott, Andrew D., Schechtman, Leonard M., Shen, Rhine R., Tanaka, Noriho, Yasaei, Hemad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Meeting Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241940/
https://www.ncbi.nlm.nih.gov/pubmed/21852270
http://dx.doi.org/10.1093/mutage/ger053

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