Cargando…
Qualitative prediction of blood–brain barrier permeability on a large and refined dataset
The prediction of blood–brain barrier permeation is vitally important for the optimization of drugs targeting the central nervous system as well as for avoiding side effects of peripheral drugs. Following a previously proposed model on blood–brain barrier penetration, we calculated the cross-section...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241963/ https://www.ncbi.nlm.nih.gov/pubmed/22109848 http://dx.doi.org/10.1007/s10822-011-9478-1 |