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Domain assembly of NAADP-gated two-pore channels

TPCs (two-pore channels) have recently been identified as targets for the Ca(2+)-mobilizing messenger NAADP (nicotinic acid–adenine dinucleotide phosphate). TPCs have a unique structure consisting of cytosolic termini, two hydrophobic domains (I and II) each comprising six transmembrane regions and...

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Detalles Bibliográficos
Autores principales: Churamani, Dev, Hooper, Robert, Brailoiu, Eugen, Patel, Sandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242506/
https://www.ncbi.nlm.nih.gov/pubmed/21992073
http://dx.doi.org/10.1042/BJ20111617