Cargando…
Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage
Elevated MPO (myeloperoxidase) levels are associated with multiple human inflammatory pathologies. MPO catalyses the oxidation of Cl(−), Br(−) and SCN(−) by H(2)O(2) to generate the powerful oxidants hypochlorous acid (HOCl), hypobromous acid (HOBr) and hypothiocyanous acid (HOSCN) respectively. The...
Autores principales: | Skaff, Ojia, Pattison, David I., Morgan, Philip E., Bachana, Rushad, Jain, Vimal K., Priyadarsini, K. Indira, Davies, Michael J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242511/ https://www.ncbi.nlm.nih.gov/pubmed/21892922 http://dx.doi.org/10.1042/BJ20101762 |
Ejemplares similares
-
The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages
por: Love, Dominic T., et al.
Publicado: (2020) -
Response of Pseudomonas aeruginosa to the Innate Immune System-Derived Oxidants Hypochlorous Acid and Hypothiocyanous Acid
por: Farrant, Katie V., et al.
Publicado: (2020) -
Hypothiocyanous Acid Disrupts the Barrier Function of Brain Endothelial Cells
por: van Leeuwen, Eveline, et al.
Publicado: (2022) -
Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis
por: Bozonet, Stephanie M., et al.
Publicado: (2023) -
A newly identified flavoprotein disulfide reductase Har protects Streptococcus pneumoniae against hypothiocyanous acid
por: Shearer, Heather L., et al.
Publicado: (2022)