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Δ133p53 is an independent prognostic marker in p53 mutant advanced serous ovarian cancer

BACKGROUND: We aimed to evaluate the clinical relevance of p53 and p73 isoforms that modulate the function of p53. METHODS: This prospective multicentre study included 154 patients with stage III and IV serous ovarian cancer. A functional yeast-based assay and subsequent sequencing were performed to...

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Detalles Bibliográficos
Autores principales: Hofstetter, G, Berger, A, Schuster, E, Wolf, A, Hager, G, Vergote, I, Cadron, I, Sehouli, J, Braicu, E I, Mahner, S, Speiser, P, Marth, C, Zeimet, A G, Ulmer, H, Zeillinger, R, Concin, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242533/
https://www.ncbi.nlm.nih.gov/pubmed/22009029
http://dx.doi.org/10.1038/bjc.2011.433