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Defects of Protein Phosphatase 2A Causes Corticosteroid Insensitivity in Severe Asthma
BACKGROUND: Corticosteroid insensitivity is a major barrier of treatment for some chronic inflammatory diseases, such as severe asthma, but the molecular mechanism of the insensitivity has not been fully elucidated. The object of this study is to investigate the role of protein phosphate 2A (PP2A),...
Autores principales: | Kobayashi, Yoshiki, Mercado, Nicolas, Barnes, Peter J., Ito, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242752/ https://www.ncbi.nlm.nih.gov/pubmed/22205926 http://dx.doi.org/10.1371/journal.pone.0027627 |
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