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Gentle Masking of Low-Complexity Sequences Improves Homology Search
Detection of sequences that are homologous, i.e. descended from a common ancestor, is a fundamental task in computational biology. This task is confounded by low-complexity tracts (such as atatatatatat), which arise frequently and independently, causing strong similarities that are not homologies. T...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242753/ https://www.ncbi.nlm.nih.gov/pubmed/22205972 http://dx.doi.org/10.1371/journal.pone.0028819 |