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Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays
Chikungunya virus (CHIKV), an alphavirus, has recently caused epidemic outbreaks and is therefore considered a re-emerging pathogen for which no effective treatment is available. In this study, a CHIKV replicon containing the virus replicase proteins together with puromycin acetyltransferase, EGFP a...
Autores principales: | Pohjala, Leena, Utt, Age, Varjak, Margus, Lulla, Aleksei, Merits, Andres, Ahola, Tero, Tammela, Päivi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242765/ https://www.ncbi.nlm.nih.gov/pubmed/22205980 http://dx.doi.org/10.1371/journal.pone.0028923 |
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