Cargando…
Tau Reduction Does Not Prevent Motor Deficits in Two Mouse Models of Parkinson's Disease
Many neurodegenerative diseases are increasing in prevalence and cannot be prevented or cured. If they shared common pathogenic mechanisms, treatments targeting such mechanisms might be of benefit in multiple conditions. The tau protein has been implicated in the pathogenesis of diverse neurodegener...
Autores principales: | Morris, Meaghan, Koyama, Akihiko, Masliah, Eliezer, Mucke, Lennart |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242771/ https://www.ncbi.nlm.nih.gov/pubmed/22206005 http://dx.doi.org/10.1371/journal.pone.0029257 |
Ejemplares similares
-
Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits
por: Harris, Julie A., et al.
Publicado: (2012) -
Tau Reduction Prevents Disease in a Mouse Model of Dravet Syndrome
por: Gheyara, Ania L, et al.
Publicado: (2014) -
Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β
por: Vossel, Keith A., et al.
Publicado: (2015) -
Tau Reduction Diminishes Spatial Learning and Memory Deficits after Mild Repetitive Traumatic Brain Injury in Mice
por: Cheng, Jason S., et al.
Publicado: (2014) -
Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson’s disease
por: Valera, Elvira, et al.
Publicado: (2015)