Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer

BACKGROUND: Well over a quarter of human breast cancers are ErbB2-driven and constitute a distinct subtype with substantially poorer prognosis. Yet, there are substantial gaps in our understanding of how ErbB2 tyrosine kinase activity unleashes a coordinated program of cellular and extracellular alt...

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Detalles Bibliográficos
Autores principales: Ortega-Cava, Cesar F., Raja, Srikumar M., Laiq, Zenab, Bailey, Tameka A., Luan, Haitao, Mohapatra, Bhopal, Williams, Stetson H., Ericsson, Aaron C., Goswami, Rasna, Dimri, Manjari, Duan, Lei, Band, Vimla, Naramura, Mayumi, Band, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243085/
https://www.ncbi.nlm.nih.gov/pubmed/22190871
http://dx.doi.org/10.4103/1477-3163.90443

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