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Mechanochemical Modeling of Dynamic Microtubule Growth Involving Sheet-to-Tube Transition

Microtubule dynamics is largely influenced by nucleotide hydrolysis and the resultant tubulin configuration changes. The GTP cap model has been proposed to interpret the stabilizing mechanisms of microtubule growth from the view of hydrolysis effects. Besides, the growth of a microtubule involves th...

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Detalles Bibliográficos
Autores principales: Ji, Xiang-Ying, Feng, Xi-Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243706/
https://www.ncbi.nlm.nih.gov/pubmed/22205994
http://dx.doi.org/10.1371/journal.pone.0029049