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Immortalization of mouse myogenic cells can occur without loss of p16(INK4a), p19(ARF), or p53 and is accelerated by inactivation of Bax
BACKGROUND: Upon serial passaging of mouse skeletal muscle cells, a small number of cells will spontaneously develop the ability to proliferate indefinitely while retaining the ability to differentiate into multinucleate myotubes. Possible gene changes that could underlie myogenic cell immortalizati...
Autores principales: | Nowak, Jonathan A, Malowitz, Jonathan, Girgenrath, Mahasweta, Kostek, Christine A, Kravetz, Amanda J, Dominov, Janice A, Miller, Jeffrey Boone |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC324393/ https://www.ncbi.nlm.nih.gov/pubmed/14711384 http://dx.doi.org/10.1186/1471-2121-5-1 |
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