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Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls
Whole-cell microbial biosensors are one of the newest molecular tools used in environmental monitoring. Such biosensors are constructed through fusing a reporter gene such as lux, gfp or lacZ, to a responsive promoter. There have been many reports of the applications of biosensors, particularly thei...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244019/ https://www.ncbi.nlm.nih.gov/pubmed/22205873 http://dx.doi.org/10.3390/s100201377 |
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author | Liu, Xuemei Germaine, Kieran J. Ryan, David Dowling, David N. |
author_facet | Liu, Xuemei Germaine, Kieran J. Ryan, David Dowling, David N. |
author_sort | Liu, Xuemei |
collection | PubMed |
description | Whole-cell microbial biosensors are one of the newest molecular tools used in environmental monitoring. Such biosensors are constructed through fusing a reporter gene such as lux, gfp or lacZ, to a responsive promoter. There have been many reports of the applications of biosensors, particularly their use in assaying pollutant toxicity and bioavailability. This paper reviews the basic concepts behind the construction of whole-cell microbial biosensors for pollutant monitoring, and describes the applications of two such biosensors for detecting the bioavailability and biodegradation of Polychlorinated Biphenyls (PCBs). |
format | Online Article Text |
id | pubmed-3244019 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-32440192011-12-28 Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls Liu, Xuemei Germaine, Kieran J. Ryan, David Dowling, David N. Sensors (Basel) Review Whole-cell microbial biosensors are one of the newest molecular tools used in environmental monitoring. Such biosensors are constructed through fusing a reporter gene such as lux, gfp or lacZ, to a responsive promoter. There have been many reports of the applications of biosensors, particularly their use in assaying pollutant toxicity and bioavailability. This paper reviews the basic concepts behind the construction of whole-cell microbial biosensors for pollutant monitoring, and describes the applications of two such biosensors for detecting the bioavailability and biodegradation of Polychlorinated Biphenyls (PCBs). Molecular Diversity Preservation International (MDPI) 2010-02-21 /pmc/articles/PMC3244019/ /pubmed/22205873 http://dx.doi.org/10.3390/s100201377 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Liu, Xuemei Germaine, Kieran J. Ryan, David Dowling, David N. Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls |
title | Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls |
title_full | Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls |
title_fullStr | Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls |
title_full_unstemmed | Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls |
title_short | Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls |
title_sort | whole-cell fluorescent biosensors for bioavailability and biodegradation of polychlorinated biphenyls |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244019/ https://www.ncbi.nlm.nih.gov/pubmed/22205873 http://dx.doi.org/10.3390/s100201377 |
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