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Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls

Whole-cell microbial biosensors are one of the newest molecular tools used in environmental monitoring. Such biosensors are constructed through fusing a reporter gene such as lux, gfp or lacZ, to a responsive promoter. There have been many reports of the applications of biosensors, particularly thei...

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Detalles Bibliográficos
Autores principales: Liu, Xuemei, Germaine, Kieran J., Ryan, David, Dowling, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244019/
https://www.ncbi.nlm.nih.gov/pubmed/22205873
http://dx.doi.org/10.3390/s100201377
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author Liu, Xuemei
Germaine, Kieran J.
Ryan, David
Dowling, David N.
author_facet Liu, Xuemei
Germaine, Kieran J.
Ryan, David
Dowling, David N.
author_sort Liu, Xuemei
collection PubMed
description Whole-cell microbial biosensors are one of the newest molecular tools used in environmental monitoring. Such biosensors are constructed through fusing a reporter gene such as lux, gfp or lacZ, to a responsive promoter. There have been many reports of the applications of biosensors, particularly their use in assaying pollutant toxicity and bioavailability. This paper reviews the basic concepts behind the construction of whole-cell microbial biosensors for pollutant monitoring, and describes the applications of two such biosensors for detecting the bioavailability and biodegradation of Polychlorinated Biphenyls (PCBs).
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spelling pubmed-32440192011-12-28 Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls Liu, Xuemei Germaine, Kieran J. Ryan, David Dowling, David N. Sensors (Basel) Review Whole-cell microbial biosensors are one of the newest molecular tools used in environmental monitoring. Such biosensors are constructed through fusing a reporter gene such as lux, gfp or lacZ, to a responsive promoter. There have been many reports of the applications of biosensors, particularly their use in assaying pollutant toxicity and bioavailability. This paper reviews the basic concepts behind the construction of whole-cell microbial biosensors for pollutant monitoring, and describes the applications of two such biosensors for detecting the bioavailability and biodegradation of Polychlorinated Biphenyls (PCBs). Molecular Diversity Preservation International (MDPI) 2010-02-21 /pmc/articles/PMC3244019/ /pubmed/22205873 http://dx.doi.org/10.3390/s100201377 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Liu, Xuemei
Germaine, Kieran J.
Ryan, David
Dowling, David N.
Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls
title Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls
title_full Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls
title_fullStr Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls
title_full_unstemmed Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls
title_short Whole-Cell Fluorescent Biosensors for Bioavailability and Biodegradation of Polychlorinated Biphenyls
title_sort whole-cell fluorescent biosensors for bioavailability and biodegradation of polychlorinated biphenyls
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244019/
https://www.ncbi.nlm.nih.gov/pubmed/22205873
http://dx.doi.org/10.3390/s100201377
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