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Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants
Memory B cells (MBCs) and long-lived plasma cells (LLPCs) persist after clearance of infection, yet the specific and nonredundant role MBCs play in subsequent protection is unclear. After resolution of West Nile virus infection in mice, we demonstrate that LLPCs were specific for a single dominant n...
Autores principales: | Purtha, Whitney E., Tedder, Thomas F., Johnson, Syd, Bhattacharya, Deepta, Diamond, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244041/ https://www.ncbi.nlm.nih.gov/pubmed/22162833 http://dx.doi.org/10.1084/jem.20110740 |
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