Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome

Epidermal Langerhans cells (LCs) extend dendrites through tight junctions (TJs) to survey the skin surface, but their immunological contribution in vivo remains elusive. We show that LCs were essential for inducing IgG(1) responses to patch-immunized ovalbumin in mice that lacked skin dendritic cell...

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Detalles Bibliográficos
Autores principales: Ouchi, Takeshi, Kubo, Akiharu, Yokouchi, Mariko, Adachi, Takeya, Kobayashi, Tetsuro, Kitashima, Daniela Y., Fujii, Hideki, Clausen, Björn E., Koyasu, Shigeo, Amagai, Masayuki, Nagao, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244045/
https://www.ncbi.nlm.nih.gov/pubmed/22143886
http://dx.doi.org/10.1084/jem.20111718

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