Cargando…
Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition
Snakebite envenoming is an important public health problem in many tropical and subtropical countries, and is considered a neglected tropical disease by the World Health Organization. Most severe cases are inflicted by species of the families Elapidae and Viperidae, and lead to a number of systemic...
Autores principales: | dos Santos, Juliana I., Cardoso, Fábio F., Soares, Andreimar M., dal Pai Silva, Maeli, Gallacci, Márcia, Fontes, Marcos R. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244394/ https://www.ncbi.nlm.nih.gov/pubmed/22205953 http://dx.doi.org/10.1371/journal.pone.0028521 |
Ejemplares similares
-
A Lys49-PLA(2) myotoxin of Bothrops asper triggers a rapid death of macrophages that involves autocrine purinergic receptor signaling
por: Tonello, F, et al.
Publicado: (2012) -
Structural and Phylogenetic Studies with MjTX-I Reveal a Multi-Oligomeric Toxin – a Novel Feature in Lys49-PLA(2)s Protein Class
por: Salvador, Guilherme H. M., et al.
Publicado: (2013) -
Structural Basis for the Inhibition of a Phospholipase A(2)-Like Toxin by Caffeic and Aristolochic Acids
por: Fernandes, Carlos A. H., et al.
Publicado: (2015) -
Synergism between Basic Asp49 and Lys49 Phospholipase A(2) Myotoxins of Viperid Snake Venom In Vitro and In Vivo
por: Mora-Obando, Diana, et al.
Publicado: (2014) -
Cytotoxicity of snake venom Lys49 PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus
por: López-Dávila, Alfredo Jesús, et al.
Publicado: (2021)