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KRAS Mutations Testing in Colorectal Carcinoma Patients in Italy: From Guidelines to External Quality Assessment
BACKGROUND: Monoclonal antibodies directed against the epidermal growth factor receptor (EGFR) have been approved for the treatment of patients with metastatic colorectal carcinoma (mCRC) that do not carry KRAS mutations. Therefore, KRAS testing has become mandatory to chose the most appropriate the...
Autores principales: | Normanno, Nicola, Pinto, Carmine, Castiglione, Francesca, Bardelli, Alberto, Gambacorta, Marcello, Botti, Gerardo, Nappi, Oscar, Siena, Salvatore, Ciardiello, Fortunato, Taddei, GianLuigi, Marchetti, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244430/ https://www.ncbi.nlm.nih.gov/pubmed/22216189 http://dx.doi.org/10.1371/journal.pone.0029146 |
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