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The Nrf1 CNC-bZIP Protein Is Regulated by the Proteasome and Activated by Hypoxia
BACKGROUND: Nrf1 (nuclear factor-erythroid 2 p45 subunit-related factor 1) is a transcription factor mediating cellular responses to xenobiotic and pro-oxidant stress. Nrf1 regulates the transcription of many stress-related genes through the electrophile response elements (EpREs) located in their pr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244438/ https://www.ncbi.nlm.nih.gov/pubmed/22216197 http://dx.doi.org/10.1371/journal.pone.0029167 |