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SuperTarget goes quantitative: update on drug–target interactions

There are at least two good reasons for the on-going interest in drug–target interactions: first, drug-effects can only be fully understood by considering a complex network of interactions to multiple targets (so-called off-target effects) including metabolic and signaling pathways; second, it is cr...

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Detalles Bibliográficos
Autores principales: Hecker, Nikolai, Ahmed, Jessica, von Eichborn, Joachim, Dunkel, Mathias, Macha, Karel, Eckert, Andreas, Gilson, Michael K., Bourne, Philip E., Preissner, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245174/
https://www.ncbi.nlm.nih.gov/pubmed/22067455
http://dx.doi.org/10.1093/nar/gkr912