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ENCODE whole-genome data in the UCSC Genome Browser: update 2012

The Encyclopedia of DNA Elements (ENCODE) Consortium is entering its 5th year of production-level effort generating high-quality whole-genome functional annotations of the human genome. The past year has brought the ENCODE compendium of functional elements to critical mass, with a diverse set of 27...

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Detalles Bibliográficos
Autores principales: Rosenbloom, Kate R., Dreszer, Timothy R., Long, Jeffrey C., Malladi, Venkat S., Sloan, Cricket A., Raney, Brian J., Cline, Melissa S., Karolchik, Donna, Barber, Galt P., Clawson, Hiram, Diekhans, Mark, Fujita, Pauline A., Goldman, Mary, Gravell, Robert C., Harte, Rachel A., Hinrichs, Angie S., Kirkup, Vanessa M., Kuhn, Robert M., Learned, Katrina, Maddren, Morgan, Meyer, Laurence R., Pohl, Andy, Rhead, Brooke, Wong, Matthew C., Zweig, Ann S., Haussler, David, Kent, W. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245183/
https://www.ncbi.nlm.nih.gov/pubmed/22075998
http://dx.doi.org/10.1093/nar/gkr1012
Descripción
Sumario:The Encyclopedia of DNA Elements (ENCODE) Consortium is entering its 5th year of production-level effort generating high-quality whole-genome functional annotations of the human genome. The past year has brought the ENCODE compendium of functional elements to critical mass, with a diverse set of 27 biochemical assays now covering 200 distinct human cell types. Within the mouse genome, which has been under study by ENCODE groups for the past 2 years, 37 cell types have been assayed. Over 2000 individual experiments have been completed and submitted to the Data Coordination Center for public use. UCSC makes this data available on the quality-reviewed public Genome Browser (http://genome.ucsc.edu) and on an early-access Preview Browser (http://genome-preview.ucsc.edu). Visual browsing, data mining and download of raw and processed data files are all supported. An ENCODE portal (http://encodeproject.org) provides specialized tools and information about the ENCODE data sets.