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Non-Negative Matrix Factorization for Learning Alignment-Specific Models of Protein Evolution

Models of protein evolution currently come in two flavors: generalist and specialist. Generalist models (e.g. PAM, JTT, WAG) adopt a one-size-fits-all approach, where a single model is estimated from a number of different protein alignments. Specialist models (e.g. mtREV, rtREV, HIVbetween) can be e...

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Detalles Bibliográficos
Autores principales: Murrell, Ben, Weighill, Thomas, Buys, Jan, Ketteringham, Robert, Moola, Sasha, Benade, Gerdus, du Buisson, Lise, Kaliski, Daniel, Hands, Tristan, Scheffler, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245233/
https://www.ncbi.nlm.nih.gov/pubmed/22216138
http://dx.doi.org/10.1371/journal.pone.0028898

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