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Non-Negative Matrix Factorization for Learning Alignment-Specific Models of Protein Evolution
Models of protein evolution currently come in two flavors: generalist and specialist. Generalist models (e.g. PAM, JTT, WAG) adopt a one-size-fits-all approach, where a single model is estimated from a number of different protein alignments. Specialist models (e.g. mtREV, rtREV, HIVbetween) can be e...
Autores principales: | Murrell, Ben, Weighill, Thomas, Buys, Jan, Ketteringham, Robert, Moola, Sasha, Benade, Gerdus, du Buisson, Lise, Kaliski, Daniel, Hands, Tristan, Scheffler, Konrad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245233/ https://www.ncbi.nlm.nih.gov/pubmed/22216138 http://dx.doi.org/10.1371/journal.pone.0028898 |
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