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Differential Effects of Pravastatin and Simvastatin on the Growth of Tumor Cells from Different Organ Sites

3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) inhibitors, commonly known as statins, may possess cancer preventive and therapeutic properties. Statins are effective suppressors of cholesterol synthesis with a well-established risk-benefit ratio in cardiovascular disease prevention. Mechani...

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Detalles Bibliográficos
Autores principales: Menter, David G., Ramsauer, Victoria P., Harirforoosh, Sam, Chakraborty, Kanishka, Yang, Peiying, Hsi, Linda, Newman, Robert A., Krishnan, Koyamangalath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245236/
https://www.ncbi.nlm.nih.gov/pubmed/22216116
http://dx.doi.org/10.1371/journal.pone.0028813