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Differential Effects of Pravastatin and Simvastatin on the Growth of Tumor Cells from Different Organ Sites
3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) inhibitors, commonly known as statins, may possess cancer preventive and therapeutic properties. Statins are effective suppressors of cholesterol synthesis with a well-established risk-benefit ratio in cardiovascular disease prevention. Mechani...
Autores principales: | Menter, David G., Ramsauer, Victoria P., Harirforoosh, Sam, Chakraborty, Kanishka, Yang, Peiying, Hsi, Linda, Newman, Robert A., Krishnan, Koyamangalath |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245236/ https://www.ncbi.nlm.nih.gov/pubmed/22216116 http://dx.doi.org/10.1371/journal.pone.0028813 |
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