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Intranasal Immunization of the Combined Lipooligosaccharide Conjugates Protects Mice from the Challenges with Three Serotypes of Moraxella catarrhalis
BACKGROUND: There are no licensed vaccines available against Moraxella catarrhalis, a significant human respiratory pathogen. Lipooligosaccharide (LOS) based conjugate vaccines derived from individual serotype M. catarrhalis only showed partial protection coverage. A vaccine combining LOS conjugates...
Autores principales: | Ren, Dabin, Xie, Hang, Zhang, Wenhong, Hassan, Ferdaus, Petralia, Ronald S., Yu, Shengqing, Lim, David J., Gu, Xin-Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245267/ https://www.ncbi.nlm.nih.gov/pubmed/22216312 http://dx.doi.org/10.1371/journal.pone.0029553 |
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