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The Mycobacterium Tuberculosis FAS-II Dehydratases and Methyltransferases Define the Specificity of the Mycolic Acid Elongation Complexes

BACKGROUND: The human pathogen Mycobacterium tuberculosis (Mtb) has the originality of possessing a multifunctional mega-enzyme FAS-I (Fatty Acid Synthase-I), together with a multi-protein FAS-II system, to carry out the biosynthesis of common and of specific long chain fatty acids: the mycolic acid...

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Detalles Bibliográficos
Autores principales:	Cantaloube, Sylvain, Veyron-Churlet, Romain, Haddache, Nabila, Daffé, Mamadou, Zerbib, Didier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245277/ https://www.ncbi.nlm.nih.gov/pubmed/22216317 http://dx.doi.org/10.1371/journal.pone.0029564

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