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Elongase Reactions as Control Points in Long-Chain Polyunsaturated Fatty Acid Synthesis

BACKGROUND: Δ6-Desaturase (Fads2) is widely regarded as rate-limiting in the conversion of dietary α-linolenic acid (18:3n-3; ALA) to the long-chain omega-3 polyunsaturated fatty acid docosahexaenoic acid (22:6n-3; DHA). However, increasing dietary ALA or the direct Fads2 product, stearidonic acid (...

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Detalles Bibliográficos
Autores principales:	Gregory, Melissa K., Gibson, Robert A., Cook-Johnson, Rebecca J., Cleland, Leslie G., James, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245304/ https://www.ncbi.nlm.nih.gov/pubmed/22216341 http://dx.doi.org/10.1371/journal.pone.0029662

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