Cargando…
Prion Uptake in the Gut: Identification of the First Uptake and Replication Sites
After oral exposure, prions are thought to enter Peyer's patches via M cells and accumulate first upon follicular dendritic cells (FDCs) before spreading to the nervous system. How prions are actually initially acquired from the gut lumen is not known. Using high-resolution immunofluorescence a...
Autores principales: | Kujala, Pekka, Raymond, Claudine R., Romeijn, Martijn, Godsave, Susan F., van Kasteren, Sander I., Wille, Holger, Prusiner, Stanley B., Mabbott, Neil A., Peters, Peter J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245311/ https://www.ncbi.nlm.nih.gov/pubmed/22216002 http://dx.doi.org/10.1371/journal.ppat.1002449 |
Ejemplares similares
-
Mechanism of Scrapie Prion Precipitation with Phosphotungstate
Anions
por: Levine, Dana J., et al.
Publicado: (2014) -
Protease-Resistant Prions Selectively Decrease Shadoo Protein
por: Watts, Joel C., et al.
Publicado: (2011) -
Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein
por: Krejciova, Zuzana, et al.
Publicado: (2019) -
Prion pathogenesis and secondary lymphoid organs (SLO): Tracking the SLO spread of prions to the brain
por: Mabbott, Neil A.
Publicado: (2012) -
How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer’s Disease and Other Neurodegenerative Disorders
por: Carlson, George A., et al.
Publicado: (2021)