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CNS Recruitment of CD8+ T Lymphocytes Specific for a Peripheral Virus Infection Triggers Neuropathogenesis during Polymicrobial Challenge

Although viruses have been implicated in central nervous system (CNS) diseases of unknown etiology, including multiple sclerosis and amyotrophic lateral sclerosis, the reproducible identification of viral triggers in such diseases has been largely unsuccessful. Here, we explore the hypothesis that v...

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Detalles Bibliográficos
Autores principales: Matullo, Christine M., O'Regan, Kevin J., Curtis, Mark, Rall, Glenn F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245314/
https://www.ncbi.nlm.nih.gov/pubmed/22216008
http://dx.doi.org/10.1371/journal.ppat.1002462