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Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes
Bacterial pathogens evolve during the infection of their human hosts(1-8), but separating adaptive and neutral mutations remains challenging(9-11). Here, we identify bacterial genes under adaptive evolution by tracking recurrent patterns of mutations in the same pathogenic strain during the infectio...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245322/ https://www.ncbi.nlm.nih.gov/pubmed/22081229 http://dx.doi.org/10.1038/ng.997 |