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Enhanced Expression of Tissue Inhibitor of Metalloproteinases-4 Gene in Human Osteoarthritic Synovial Membranes and Its Differential Regulation by Cytokines in Chondrocytes

OBJECTIVE: Tissue inhibitors of metalloproteinases (TIMPs) are multi-functional proteins with matrix metalloproteinases-inhibiting activities. We studied expression of anti-inflammatory, TIMP-4 gene in human joint tissues and its regulation by arthritis-associated cytokines. RESULTS: TIMP-4 RNA expr...

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Detalles Bibliográficos
Autores principales:	Huang, Wensheng, Mabrouk, Mohammed El, Sylvester, Judith, Dehnade, Faramaze, Zafarullah, Muhammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245407/ https://www.ncbi.nlm.nih.gov/pubmed/22216069 http://dx.doi.org/10.2174/1874312901105010081

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