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T cell receptor transgenic lymphocytes infiltrating murine tumors are not induced to express foxp3

Regulatory T cells (Treg) that express the transcription factor Foxp3 are enriched within a broad range of murine and human solid tumors. The ontogeny of these Foxp3 Tregs - selective accumulation or proliferation of natural thymus-derived Treg (nTreg) or induced Treg (iTreg) converted in the periph...

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Detalles Bibliográficos
Autores principales: Quatromoni, Jon G, Morris, Lilah F, Donahue, Timothy R, Wang, Yue, McBride, William, Chatila, Talal, Economou, James S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245424/
https://www.ncbi.nlm.nih.gov/pubmed/22112546
http://dx.doi.org/10.1186/1756-8722-4-48