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Synthesis of an antiviral drug precursor from chitin using a saprophyte as a whole-cell catalyst

BACKGROUND: Recent incidents, such as the SARS and influenza epidemics, have highlighted the need for readily available antiviral drugs. One important precursor currently used for the production of Relenza, an antiviral product from GlaxoSmithKline, is N-acetylneuraminic acid (NeuNAc). This substanc...

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Detalles Bibliográficos
Autores principales: Steiger, Matthias G, Mach-Aigner, Astrid R, Gorsche, Rita, Rosenberg, Erwin E, Mihovilovic, Marko D, Mach, Robert L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245449/
https://www.ncbi.nlm.nih.gov/pubmed/22141613
http://dx.doi.org/10.1186/1475-2859-10-102