Proto-oncogene CT10-regulated kinase (CRK) is a pro-apoptotic transducer of endoplasmic reticulum stress

Excessive demands on the protein folding capacity of the endoplasmic reticulum (ER) cause irremediable ER stress and contribute to cell loss in a number of cell degenerative diseases, including type 2 diabetes and neurodegeneration(1,2). The signals communicating catastrophic ER damage to the mitoch...

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Detalles Bibliográficos
Autores principales: Austgen, Kathryn, Johnson, Emily T., Park, Tae-Ju, Curran, Tom, Oakes, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245775/
https://www.ncbi.nlm.nih.gov/pubmed/22179045
http://dx.doi.org/10.1038/ncb2395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245775/
https://www.ncbi.nlm.nih.gov/pubmed/22179045
http://dx.doi.org/10.1038/ncb2395

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