Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells

We present evidence that the cisplatin-resistant human ovarian cancer lines, A2780S/CP1 (S/CP1), A2780S/CP3 (S/CP3), and A2780S/CP5 (S/CP5), derived by subjecting the sensitive A2780S ovarian cancer line to multiple rounds of cisplatin treatments followed by recovery and are resistant to 1, 3, and 5...

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Detalles Bibliográficos
Autores principales: Yue, Peibin, Zhang, Xiaolei, Paladino, David, Sengupta, Bhaswati, Ahmad, Sarfraz, Holloway, Robert W., Ingersoll, Susan B., Turkson, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245777/
https://www.ncbi.nlm.nih.gov/pubmed/21909139
http://dx.doi.org/10.1038/onc.2011.409

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